Simulation methods · 6 min read
When to simulate instead of calculate
Introductory paragraph setting up the problem, why it matters for trial designers, and what the reader will learn.
Why this matters
Briefly connect the topic to real trial planning decisions, such as sample size, timelines, or governance thresholds.
Core idea
Use 2–3 short paragraphs or bullet points to explain the main concept in plain language, with minimal notation.
Practical takeaways
- When to apply this in protocol design.
- Common pitfalls or misinterpretations to avoid.
- How simulation can make the trade‑offs visible.